Estrogen, a feminine hormone, is recognized to have joint supporting cartilage-protecting properties. This is why women have a tendency to experience joint pain following menopause when estrogen levels go down. It is also the purpose why some ladies experience joint pain at the onset of menstruation when estrogen levels plummet. Joint supplements that contain glucosamine, taken regularly, can help alleviate the inner effects of hormonal fluctuations on joint well being. Anti-getting older is not just pores and skin deep.